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Abstract
Shift work is associated with an increased stroke risk due to disruptions in .
- Circadian rhythm disruptions affect the functioning of endothelial cells, which can lead to blood pressure issues.
- Night shifts are significantly linked to type 2 diabetes, impacting glucose metabolism and insulin sensitivity.
- Melatonin production is disrupted in shift workers, affecting insulin and glucose balance.
- , particularly lower levels of HDL cholesterol, is a consequence of shift work and may contribute to stroke risk.
- High lipid levels can lead to oxidative stress and inflammation, which increase risks for cerebrovascular events.
- The interplay of circadian disruption, hypertension, diabetes, and dyslipidemia complicates stroke vulnerability in shift workers.
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