Circadian clock genes and the transcriptional architecture of the clock mechanism

Sep 27, 2019Journal of molecular endocrinology

Genes Controlling the Body’s Internal Clock and How They Regulate Its Activity

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Abstract

The mammalian circadian clock helps synchronize cellular activities with the 24-hour light/dark cycle.

  • Circadian clocks are crucial for coordinating physiological processes like eating and sleeping.
  • Cells utilize a core set of clock genes to regulate networks of gene activity.
  • These clock genes influence gene transcription directly and also recruit proteins that alter chromatin structure.
  • The full mechanisms of how cells maintain their circadian clock are still being explored.

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