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Circadian clocks in the digestive system
Body Clock Rhythms in the Digestive System
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Abstract
Circadian clocks are involved in the regulation of gastrointestinal processes.
- The master clock in the hypothalamus synchronizes with light-dark cycles and feeding times.
- Peripheral clocks in the digestive tract influence digestion, motility, hormone levels, and gut barrier function.
- Circadian rhythms may regulate the gut microbiota and its interactions with the digestive system.
- Different circadian clocks in the digestive system are implicated in glucose and lipid metabolism.
- Behavioral adjustments or pharmacological strategies could help mitigate adverse effects of chronodisruption.
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