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Interaction of central and peripheral clocks in physiological regulation
How internal body clocks in the brain and organs work together to control body functions
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Abstract
Circadian rhythms in mammals are influenced by both a master clock in the hypothalamic suprachiasmatic nuclei (SCN) and peripheral clocks throughout the body.
- The SCN synchronizes internal biological time with the external light-dark cycle.
- Recent findings suggest that the SCN may not be the sole regulator of physiological processes.
- Communication between central and peripheral clocks is essential for maintaining stable circadian rhythms.
- Interactions between different clocks may influence glucocorticoid release from the adrenal gland.
- These interactions also play a role in regulating glucose levels in the blood.
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