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Peripheral Circadian Oscillators in Mammals
Body clocks outside the brain in mammals
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Abstract
Circadian rhythms are governed by a biological clock that operates autonomously in nearly all cells of the body.
- The suprachiasmatic nuclei (SCN) acts as a 'master clock' coordinating other 'slave' clocks in peripheral tissues.
- Peripheral clocks have distinct mechanisms compared to the SCN, influencing their respective functions.
- Peripheral tissues can be synchronized to the SCN and environmental cues through various mechanisms.
- Peripheral oscillators are involved in regulating circadian physiology in different cells and tissues.
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