[Clock genes and clock-controlled genes in mammals].

Aug 1, 2012Nihon rinsho. Japanese journal of clinical medicine

Genes that control daily biological rhythms in mammals

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Abstract

Hundreds of tissue-specific circadian genes have been identified that regulate various biological processes.

  • The suprachiasmatic nucleus (SCN) serves as the primary circadian pacemaker in mammals.
  • Oscillatory mechanisms associated with clock genes function in both peripheral organs and isolated cells.
  • Circadian clocks operate through a transcriptional-translational mechanism present in the SCN and peripheral cells.
  • Recent research highlights the complexity and diversity of biological processes influenced by circadian genes.

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