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Regulation and function of extra‐SCN circadian oscillators in the brain
Control and role of brain clocks outside the main circadian center
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Abstract
Circadian clocks evolved in most organisms to adapt to 24-hour environmental changes.
- Circadian clocks are internal mechanisms that help organisms respond to daily environmental variations.
- The mammalian circadian clock system consists of cellular oscillators in all body tissues, organized hierarchically.
- A master pacemaker in the suprachiasmatic nucleus (SCN) coordinates the timing of peripheral tissue clocks.
- Various external cues, known as Zeitgebers, can reset the circadian clock system through the SCN or directly at the tissue level.
- Non-SCN brain oscillators, which are less studied, are influenced by the SCN and may have unique physiological roles.
- Understanding extra-SCN oscillators could provide insights into the overall organization of the circadian clock network in the brain.
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