Body’s internal clocks in the adrenal glands and how adrenal hormones help control daily body rhythms

Circadian rhythms of adrenal hormones can significantly influence physiological processes.

• The suprachiasmatic nucleus (SCN) serves as the primary pacemaker for the mammalian circadian timing system.
• Peripheral tissue clocks, including those in the adrenal gland, contribute to the regulation of various physiological processes.
• Adrenal hormones exhibit strong circadian secretion rhythms that affect downstream physiological functions.
• Circadian clocks in the adrenal gland may be reset by the SCN and can relay time-of-day information to other tissues.
• Disruption of adrenal hormone rhythms is associated with neuropsychiatric, metabolic, immune, and malignant disorders.

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