Science (New York, N.Y.)

How daily body clocks and sleep relate to brain cell damage in neurodegeneration

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

Disruptions in circadian rhythms and sleep cycles may significantly impact health as people age.

  • Circadian and sleep disturbances could drive the early onset of neurodegenerative diseases.
  • There is an interplay between central and peripheral circadian rhythms and their impact on brain health.
  • Circadian clock gene function is associated with maintaining brain balance and homeostasis.
  • The influence of circadian rhythms and sleep on neurodegeneration suggests potential avenues for promoting healthy brain aging.

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