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Associations between circadian disruption and cardiometabolic disease risk: A review
Links between disrupted body clocks and heart and metabolism disease risk
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Abstract
Circadian disruption is associated with adverse health outcomes, including higher BMI and blood pressure.
- Disruption of circadian rhythms can negatively impact cardiometabolic health.
- Five factors identified that may disrupt circadian rhythm alignment: shift work, late chronotype, late sleep timing, sleep irregularity, and late meal timing.
- Observational studies indicate a correlation between circadian disruptors and increased risks of obesity, hypertension, dyslipidemia, inflammation, and diabetes.
- Future research is needed to determine specific pathways that underlie health consequences associated with shift work.
- Optimal sleep and meal timing may improve metabolic health and warrant exploration in future intervention studies.
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