Can the circadian phase be estimated from self-reported sleep timing in patients with Delayed Sleep Wake Phase Disorder to guide timing of chronobiologic treatment?

Self-reported sleep timing estimates the circadian phase within ±1.5 hours for 88% of individuals with Delayed Sleep Wake Phase Disorder.

• Significant positive correlations were found between self-reported sleep timing and measured circadian phase markers, including dim-light melatonin onset, core body temperature minimum, and midpoint of melatonin secretion.
• The combination of multiple sleep timing measures provided the most accurate predictions of circadian phase.
• Self-reported midsleep and sleep onset times also demonstrated strong predictive value for estimating circadian phase, with 83% and 79% accuracy, respectively.
• These results indicate that using self-reported sleep timing could be a cost-effective method for guiding treatment in individuals with Delayed Sleep Wake Phase Disorder.

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