Circadian Rhythms of C‐FOS Expression in the Suprachiasmatic Nuclei of the Common Vole (Microtus arvalis)

Jul 16, 2008Chronobiology international

Daily patterns of activity in the brain’s internal clock of the common vole

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Abstract

In the common vole, rhythmic c-Fos expression in the dorsomedial SCN peaks during the light period under a 12:12 light/dark cycle.

  • C-FOS expression in the dorsomedial SCN is rhythmic under light/dark conditions but becomes non-rhythmic under constant dim light.
  • The pattern of C-FOS expression in voles may indicate a weak circadian organization of behavioral activity.
  • In the ventrolateral SCN, C-FOS expression rises before lights-on and peaks at both lights-on and lights-off.
  • The timing of peaks in ventrolateral C-FOS expression does not shift with changes in the light schedule, suggesting an internal process may regulate expression.

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