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Physiological links between circadian rhythms, metabolism and nutrition
How Body Clocks, Metabolism, and Nutrition Are Connected
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Abstract
Circadian rhythms are linked to metabolism and nutrition, with targeted disruption of circadian clocks showing effects in mouse models.
- Circadian rhythms and metabolic physiology influence each other.
- Novel feedback loops connect circadian clock genes to nuclear receptor expression and major metabolic pathways.
- Mouse models reveal the role of tissue-specific circadian clocks in regulating glucose levels and body weight.
- Obesity is associated with complex changes in circadian rhythms, which may vary among individuals.
- Meal timing and nutritional composition can influence circadian rhythms, especially in peripheral tissues.
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