Expanding the connection between daily body clocks and cellular energy balance in gene regulation

Circadian rhythms significantly influence oxidative stress and redox balance.

• Circadian rhythms regulate numerous genes through changes in the epigenome.
• Oxidative stress and redox balance are linked to circadian control.
• Disruptions in circadian rhythms may lead to increased oxidative stress.
• Alterations in the epigenomic landscape are associated with disruptions of the circadian clock.
• Evidence suggests potential connections between the circadian clock and redox metabolism via epigenetic mechanisms.

Simplified