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Abstract
Circadian genes and rhythmic physiologic activities have been identified in .
- are present in almost all cells, but their role in stem cells is not fully established.
- The circadian clock is often associated with differentiated cells rather than immature embryonic stem cells.
- Evidence suggests that stem cells exhibit circadian gene expression and characteristics in their extracellular vesicles.
- Circadian rhythms may influence various physiological and pathological mechanisms related to cell fate.
- Integrating circadian rhythms into clinical applications could potentially improve outcomes in stem cell-based regenerative medicine.
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