Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Guidelines for Treating Natural Sleep-Wake Cycle Disorders: Early, Delayed, Non-24-Hour, and Irregular Sleep Patterns

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

Strategically timed melatonin is positively endorsed for treating intrinsic circadian rhythm sleep-wake disorders in select populations.

  • Melatonin is recommended for adults with delayed sleep-wake phase disorder (DSWPD), blind adults with non-24-hour sleep-wake disorder (N24SWD), and children/adolescents with irregular sleep-wake rhythm disorder (ISWRD) and neurological comorbidities.
  • Light therapy, with or without behavioral interventions, is suggested for adults with advanced sleep-wake phase disorder (ASWPD), children/adolescents with DSWPD, and elderly individuals with dementia.
  • Recommendations against melatonin use are made for elderly patients with dementia, supported by a first-tier degree of confidence.
  • No recommendations were given for other treatments due to insufficient or absent data, highlighting gaps in current research.

Simplified

Full Text

Full text is available at the source.
View Full Text ↗

Related papers

Jun '16
Body Clock Melatonin and Temperature Timing in Patients with Delayed Sleep Phase and Non-24-Hour Sleep Disorders
cited by 54 papers
journal article
Jul '20
Differences in internal body clock timing and sleep patterns in delayed sleep phase disorder and sighted non-24-hour sleep rhythm disorder
top 10% journal
cited by 21 papers
research support, non-u.s. gov't
Apr '17
Using skin cells to study body clock patterns in people with sleep timing disorders
top 5% journal
cited by 25 papers
research support, non-u.s. gov't
Feb '17
Personality differences in people with delayed and non-24-hour sleep timing compared to healthy sleepers
cited by 27 papers
journal article
Nov '18
Using Light to Treat Sleep-Wake Cycle Disorders
top 20% journal
cited by 10 papers
journal article
Nov '07
Guidelines for Diagnosing and Treating Sleep Problems Caused by Body Clock Disorders
cited by 514 papers
practice guideline
Jul '18
Using Activity Trackers to Assess Sleep and Body Clock Disorders: Clinical Guidelines
cited by 391 papers
practice guideline
Sep '20
Impaired light detection by special eye cells in delayed sleep phase and sighted non-24-hour sleep disorders
top 10% journal
cited by 37 papers
research support, non-u.s. gov't
Aug '17
Sleep-Wake Problems Caused by Disrupted Body Clocks
top 20% journal
cited by 48 papers
research support, non-u.s. gov't
Nov '15
Non-24-Hour Sleep-Wake Rhythm Disorder in People with and without Sight
top 10% journal
cited by 59 papers
journal article

what lands in your inbox each week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • ✅direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free

Recent issues from the circadian biology brief

issue #44
Sleeping late on weekends is independently linked to higher cardiovascular disease risk
yesterday7 studies
issue #43
A smartphone app cut mood episode recurrence 3.4x in people with depression and bipolar disorder
1 week ago7 studies
issue #42
Morning cancer immunotherapy linked to 49% vs 40% disease control rate in 969 patients
2 weeks ago7 studies
issue #41
Timing cancer treatment before 3pm nearly doubled survival in lung cancer patients
3 weeks ago7 studies
issue #40
Male mice lived 12% longer when they ate only during an 8-hour window at night
4 weeks ago7 studies
issue #38
Emergency doctors had 67% higher odds of chronic pain when working evening shifts vs. morning shifts
6 weeks ago7 studies
issue #36
Night owls show 77% higher risk of job burnout among firefighters
8 weeks ago7 studies
issue #35
Bacteria exposure resets your internal clock independently of immune responses
9 weeks ago7 studies
issue #34
Night owl teens got 47 minutes more sleep with bright light glasses
10 weeks ago7 studies
issue #33
Working out at your optimal time cuts blood pressure twice as much
11 weeks ago7 studies
explore the archive
See more issues from the circadian biology brief