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Clock genes, ADHD and aggression
Links between body clock genes, ADHD, and aggressive behavior
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Abstract
Attention deficit/hyperactivity disorder (ADHD) is frequently associated with comorbid aggression and sleep disturbances.
- The circadian system, which regulates the sleep/wake cycle, is influenced by clock genes.
- Clock genes can affect the breakdown of neurotransmitters through their regulation of monoamine oxidase A.
- Alterations in the interaction between monoamines and clock genes may contribute to ADHD and related aggressive behaviors.
- Changes in circadian rhythms have been linked to aggressive behavior and variations in clock gene expression.
- Further research is necessary to clarify the role of clock genes in ADHD patients with comorbid aggression and sleep disturbances.
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