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Abstract
Time-restricted eating (TRE) limits daily meals to a window of 6-12 hours and may reduce cardiometabolic disease risks.
- TRE consolidates circadian rhythms of metabolism and physiology.
- Canonical circadian clocks are not necessary for TRE's effects in the liver.
- Meal timing influences circadian rhythms in different tissues in a tissue-specific manner.
- The liver and fat tissue respond readily to meal timing, while the heart and kidneys show resistance.
- Identifying clock-modulated checkpoints (CCPs) could clarify how tissues respond to TRE.
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