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Comparative efficacy of 200 mg versus 1200 mg of simethicone with 3 L polyethylene glycol electrolyte solution for afternoon colonoscopy: a randomized controlled trial
Comparing 200 mg and 1200 mg Simethicone with 3 L Bowel Cleanser for Afternoon Colonoscopy
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Abstract
A total of 668 participants were included in a comparison of 200 mg and 1200 mg of simethicone added to a bowel preparation solution.
- Both doses of simethicone resulted in similar rates of adequate bowel preparation (95.8% for 200 mg vs. 97.6% for 1200 mg, P = 0.276).
- The was comparable between the two groups (22.3% for 200 mg vs. 25.6% for 1200 mg, P = 0.561).
- Participants tolerated and accepted both regimens well, with no significant adverse events related to bowel preparation reported.
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Key numbers
95.8%
Adequate Bowel Preparation Rate
200 mg SIM group rate compared to 1200 mg group rate of 97.6%.
22.3%
()
Compared to 25.6% in the 1200 mg SIM group.
85.8%
Participant Willingness for Future Use
Willingness in the 200 mg SIM group compared to 84.5% in the 1200 mg group.