Journal of psychopharmacology (Oxford, England)Jul 9, 2026

DMT may improve anxiety, life satisfaction, and quality of life in healthy people and those with depression beyond just reducing symptoms

Psychedelic Science Weekly Brief ↗PubMed ↗DOI ↗

Updated Jul 10, 2026

Abstract

Rapid antidepressant effects of inhaled N,N-dimethyltryptamine (DMT) have been observed in recent studies.

Long-term effects of DMT on mental health and overall well-being remain largely unexplored.
Limited research exists on the broader impacts of DMT across diverse populations.
Further investigation is needed to understand the sustainability of DMT's antidepressant effects.

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