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Drug delivery to brain tumors
Getting medicine into brain tumors
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Abstract
Overcoming the blood-brain barrier is essential for effective drug delivery to brain tumors.
- Therapeutic concentrations of cancer drugs are often not achieved in systemic solid tumors due to various internal factors.
- In brain cancer, the blood-brain barrier and blood-cerebrospinal fluid barrier pose significant challenges to drug delivery.
- Multiple strategies are being investigated to improve drug delivery to brain tumors, including high-dose intravenous chemotherapy and intra-arterial drug delivery.
- Local drug delivery methods, such as implanted polymers or catheters, are also under active examination.
- Techniques aimed at disrupting the blood-brain barrier or modifying drug properties may facilitate enhanced treatment options.
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