Electroacupuncture may improve sugar and fat metabolism problems in obese mice by affecting the FXR pathway

Electroacupuncture may regulate glycolipid metabolism and improve obesity by activating specific signaling pathways.

• Activation of the farnesoid X receptor (FXR) and takeda G protein-coupled receptor 5 (TGR5) pathways is associated with changes in glycolipid metabolism.
• The glucagon-like peptide-1 (GLP-1) signaling pathway may be involved in the effects of electroacupuncture on obesity.
• The fibroblast growth factor 15 (FGF15) pathway could also play a role in mediating the impact of electroacupuncture on weight regulation.
• The findings are based on observations in obese mice induced by a high-fat diet.

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