Exercise training reduces poor glucose control caused by fat removal surgery in rats

The exercised plus lipectomized group demonstrated greater insulin sensitivity compared to all other groups.

• Partial removal of visceral adipose tissue may improve insulin action.
• Short-term swimming training was associated with lower fasting insulin levels in exercised groups.
• Impaired glucose tolerance and increased TNF-alpha gene expression were observed in sedentary lipectomized animals.
• Body weight and fat mass did not differ among the groups after the interventions.
• Exercise combined with lipectomy could potentially enhance insulin sensitivity despite fat regain.

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