Molecular biology reports

Designing cell-made delivery packages for gene therapy: new genetic approaches and future possibilities

Updated

Abstract

Extracellular vesicles (EVs) may serve as effective biological nanocarriers for gene therapy.

  • EVs can transport nucleic acids, proteins, and lipids between cells.
  • Recent advancements reveal complex processes involved in EV formation and cargo selection.
  • Modern genetic technologies allow for precise alterations of EV content and function.
  • Engineering strategies are being developed to enhance the targeting and therapeutic potential of EVs.
  • Challenges including vesicle diversity, large-scale production, and clinical application remain significant.
  • Future developments may enable EVs to play a crucial role in personalized medicine.

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Funding

Competing interests

0 of 9
authors report competing interests
9 report none
PubMed

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