Current topics in medicinal chemistryMar 6, 2024

Key Fluorine-Containing Drugs Approved by the U.S. FDA in 2023

Alzheimers & Treatments Weekly Brief ↗PubMed ↗DOI ↗

Updated Mar 31, 2026

Abstract

Twelve drugs approved by the FDA in 2023 contain fluorine.

Fluorine's role in drug development is becoming increasingly significant.
The review details each fluorinated drug's brand name, approval date, and composition.
Information on sponsors, indications, and mechanisms of action for these drugs is included.
Future trends in the application of fluorine in pharmaceuticals are discussed.

Simplified

Fluorine continues to show its potential applications in drug discovery and development, as reflected by twelve drugs being fluorinated out of the fifty-five approved by the FDA in 2023. This concise review highlights the discovery of each of these fluorine-containing drugs in the past year, including its brand name, date of approval, composition, sponsors, indication, and mechanism of action. The relevant future trend is also briefly discussed.

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Key Fluorine-Containing Drugs Approved by the U.S. FDA in 2023

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