Fluorine‐Containing Drugs Approved by the FDA in 2018

May 18, 2019Chemistry (Weinheim an der Bergstrasse, Germany)

Fluorine-Based Drugs Approved by the FDA in 2018

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Abstract

In 2018, 17 fluorine-containing drugs were approved by the FDA.

  • Fluorine substitution is a key feature in about half of the most successful drugs.
  • The reviewed drugs include various types of aromatic and aliphatic fluorine and carbon-fluorine substitutions.
  • These drugs represent advancements in treating diseases such as cancer, HIV, malaria, and smallpox.
  • Fluorine atoms enhance the structural properties of pharmaceuticals, contributing to their effectiveness.

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