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Association of the FTO fat mass and obesity–associated gene rs9939609 polymorphism with rewarding value of food and eating behavior in Chilean children
Link between a common obesity gene variant and food reward and eating habits in Chilean children
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Abstract
Allelic frequencies of rs9939609 were found to be 77% for the A allele and 23% for the T allele in a study of 258 Chilean children.
- Normal-weight girls carrying the A allele had higher scores in Satiety Responsiveness and Slowness.
- Normal-weight boys with the A allele exhibited higher Negative Affect and lower Desire to Drink scores.
- Overweight A carriers showed increased Food Responsiveness, Emotional Overeating, Enjoyment of Food, and Food Choice scores, alongside lower Satiety Responsiveness and Slowness scores.
- Obese children with the A allele had higher Cognitive Restraint scores and lower Food Choice scores.
- The A allele of rs9939609 in the FTO gene is associated with specific eating behavior traits, which may predispose individuals to obesity.
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