Robustness of gene expression rhythmicity can identify new oscillator components in the circadian clock

Many eukaryotic genomes exhibit rhythmic gene expression with peak activity at specific times of the day.

• Circadian clock genes in plants can affect the timing and duration of gene expression when expressed incorrectly.
• The identification of plant circadian clock components has evolved over the past 30 years through genetic studies.
• Mathematical modeling has improved the understanding of how these clock genes interact and respond to environmental factors.
• The complexity of the circadian clock suggests that more components may still be identified.
• Current research is focusing on how clock genes regulate cellular and physiological processes in response to environmental changes.
• Transcriptome studies enable the identification of new oscillator components by analyzing genes with strong rhythmic expression patterns.

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