Diabetes, obesity & metabolism

Mental Health Safety of GLP-1 and Dual GIP/GLP-1 Treatments in Obese Adolescents

Updated

Abstract

Concerns regarding psychiatric adverse events, particularly suicidality, are associated with the use of GLP-1 receptor agonists in adolescents.

  • GLP-1 receptor agonists (GLP-1RAs) and dual GIP/GLP-1 receptor agonists are commonly prescribed for adolescent obesity.
  • There is increasing usage of these medications among this population.
  • Psychiatric adverse events, including suicidality, remain a significant concern.
  • Monitoring for these adverse events is crucial as their prevalence may impact treatment decisions.

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