JAMAAug 20, 2026

GLP-1 Gut Hormones: From Discovery to Major Public Health Impact – A Conversation with Jens Juul Holst and Lotte Bjerre Knudsen

GLP-1 Therapies Weekly Brief ↗PubMed ↗DOI ↗

Updated Aug 21, 2026

Abstract

The origins of glucagon-like peptide-1s (GLP-1s) are discussed.

GLP-1s are important hormones involved in glucose metabolism.
They may play a role in appetite regulation.
Recent discussions focus on their potential therapeutic uses.
Future directions for research on GLP-1s could explore new treatment options.

Simplified

The origins of glucagon-like peptide-1s (GLP-1s) and what comes next are discussed by JAMA Senior Editor Derek C. Angus, MD, MPH, and Jens Juul Holst, MD, DMSc, a professor of medical physiology at the University of Copenhagen, and Lotte Bjerre Knudsen, DMSc, professor, for the Healthy Dialogue podcast.

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GLP-1 Gut Hormones: From Discovery to Major Public Health Impact – A Conversation with Jens Juul Holst and Lotte Bjerre Knudsen

Abstract

Full Text

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