BMJ open

Link between GLP-1 receptor drugs and alcohol-related hospital visits in adults with alcohol use disorder

Updated

Abstract

The study evaluates the association between newer glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and alcohol-related hospitalizations.

  • Newer GLP-1 RAs, including semaglutide and tirzepatide, may be linked to hospitalizations due to alcohol use.
  • The analysis focuses on adults with both alcohol use disorder and type 2 diabetes or obesity.
  • The study employs a retrospective cohort design using target trial emulation.

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Full Text

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Funding

Competing interests

Competing interests: PJR is a former employee of Truveta and a current employee of Eli Lilly. This work was conducted and submitted prior to her employment with Eli Lilly. Eli Lilly had no role in this study. JBL declares relevant committee service (unpaid) for the American Heart Association and grant funding from the American Heart Association (NA). HM received research funding from the National Institute on Aging (K01AG070329). APK receives research funding from the American Heart Association (NA). EH and EW are employees of Truveta, which provides access to the data used in this study. DD and NS are former employees of Truveta. All other authors declare no competing interests.
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