Canadian journal of physiology and pharmacology

How Gut Hormone Drugs and Gut Bacteria May Interact to Affect Weight Loss

Updated

Abstract

Limited research exists on the interactions between glucagon-like peptide-1 receptor agonists and the gut microbiome.

  • Glucagon-like peptide-1 receptor agonists may influence body weight and dietary habits.
  • Changes in behavior and diet are suggested to drive alterations in the gut microbiome following treatment with GLP-1 RAs.
  • Significant gaps in knowledge exist regarding the role of diet in the effects of GLP-1 RA therapy on the gut microbiome.
  • Proposed relationships between GLP-1 RAs, the gut microbiome, and obesity management require further investigation.

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Full Text

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Funding

Competing interests

The authors declare there are no competing interests.
PubMed

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