Frontiers in endocrinology

Effectiveness and safety of oral GLP-1 medicines for type 2 diabetes and obesity

Updated

Abstract

This meta-analysis evaluated the efficacy and safety of oral small-molecule glucagon-like peptide-1 receptor agonists (GLP-1RAs) in type 2 diabetes and obesity.

  • Efficacy of GLP-1RAs in managing blood sugar levels in type 2 diabetes may be supported by aggregated data.
  • Oral GLP-1RAs could be associated with weight loss in individuals with obesity.
  • Safety profiles for these medications are assessed, indicating potential side effects.
  • The analysis includes results from multiple studies, enhancing the reliability of findings.

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Full Text

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Funding

Competing interests

No commercial or financial ties reported.
PubMed

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