Ophthalmology. Retina

Use of GLP-1 Drugs and Risk of Sudden Optic Nerve Damage in People with Type 2 Diabetes

Updated

Abstract

Concerns exist about a potential increased risk of non-arteritic ischemic optic neuropathy (NAION) linked to glucagon-like peptide 1 receptor agonist (GLP-1 RA) use.

  • Inconsistent findings have been reported regarding the association between GLP-1 RA use and NAION risk.
  • Variability in indications for drug use may contribute to differing outcomes across studies.
  • Differences in comparator groups and follow-up periods could affect the assessment of risk.
  • The study populations examined show considerable diversity, complicating the interpretation of results.

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