JPEN. Journal of parenteral and enteral nutrition

Using Glucagon-Like Peptide-1 Medicines to Manage High Output Stoma in Adults

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Abstract

Glucagon-like peptide-1 (GLP-1) analogues may offer a new treatment option for high output stoma complications.

  • High output stoma is a significant complication following intestinal resection in patients with an enterostomy or enterocutaneous fistula.
  • Conventional treatments for high output stoma are limited and often ineffective.
  • GLP-1 analogues are being explored for their potential to influence gastrointestinal motility.
  • A defined stepwise treatment approach for managing high output stoma has not yet been established.

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