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The Efficacy of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists for Insufficient Weight Loss or Regain After Metabolic/Bariatric Surgery: A Systematic Review and Meta-analysis
How Well GLP-1 Receptor Drugs Help with Poor Weight Loss or Weight Gain After Weight-Loss Surgery
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Abstract
GLP-1 receptor agonists have a moderate effect on weight loss after metabolic and bariatric surgery, with a Cohen's d-score of 0.470.
- Patients may experience insufficient weight loss or weight regain following metabolic and bariatric surgery.
- Glucagon-like peptide-1 receptor agonists are associated with appetite suppression, slowed gastric emptying, and fat loss.
- The pooled analysis indicates that GLP-1 agonists could be effective for addressing weight issues post-surgery.
- Further research is suggested to evaluate the role of GLP-1 agonists as part of standard care for these patients.
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