Stopping a diabetes drug for two weeks around surgery and its link to leftover stomach contents during upper digestive tract exams

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) may increase the risk of retained gastric contents (RGC).

• GLP-1RAs are known to slow gastric emptying.
• Retained gastric contents could pose a risk during medical procedures.
• The optimal duration for stopping GLP-1RAs before esophagogastroduodenoscopy (EGD) is not well established.
• Discontinuation timing may impact patient safety during sedation or general anesthesia.

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