Glucagon-Like Peptide 1 Drugs, Death Rates, and Heart Health in Serious Mental Illness

Bipolar disorder, major depressive disorder, and schizophrenia are associated with substantial excess mortality, primarily due to cardiovascular disease.

• Individuals with bipolar disorder, major depressive disorder, and schizophrenia face higher mortality rates compared to the general population.
• The primary cause of this excess mortality is linked to cardiovascular disease.
• Addressing cardiovascular health in these populations may be essential for reducing overall mortality rates.

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