Glucagon-Like Peptide-1 Receptor Agonists in the Peri-Operative Period

Jan 25, 2025British journal of hospital medicine (London, England : 2005)

Use of Glucagon-Like Peptide-1 Receptor Agonists Around the Time of Surgery

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Abstract

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may be associated with an increased risk of pulmonary aspiration due to drug-induced gastroparesis.

  • GLP-1 RAs are becoming significant in treating Type 2 Diabetes Mellitus and obesity.
  • Concerns have been raised regarding the potential for pulmonary aspiration in patients using these medications.
  • The link between GLP-1 RAs and pulmonary aspiration is not definitively established.
  • Current evidence suggests a need for cautious management of patients on GLP-1 RAs.

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