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Abstract
Glucagon-like peptide-1 (GLP-1) is a hormone that enhances glucose-dependent insulin secretion and is associated with cardiovascular benefits.
- GLP-1 is mainly produced by intestinal L cells after meals and plays a role in regulating appetite and inhibiting glucagon secretion.
- Its receptor, GLP-1R, is a type of protein widely found in the cardiovascular system.
- The signaling pathways activated by GLP-1R may contribute to cardiovascular protection, although the exact molecular mechanisms remain unclear.
- Recent research has explored the structure, distribution, and expression of GLP-1R in relation to cardiovascular health.
- Developments in GLP-1 receptor agonist therapies show potential for cardiovascular applications.
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