Endocrinology

How Glucagon-Like Peptide 1 Receptor Works in the Brain's Emotion Center

Updated

Abstract

The central nucleus of the amygdala (CeA) may mediate GLP-1 receptor agonist-driven reduced food intake.

  • GLP-1 receptor activation in the CeA has been demonstrated in multiple species.
  • Different routes of administration can activate GLP-1 receptors in the CeA.
  • The specific functions of GLP-1 receptors in the CeA remain unclear.
  • Site-specific GLP-1 receptors may influence various behaviors and physiological responses related to food intake.
  • Future research directions are proposed to further investigate the role of the CeA in GLP-1 receptor actions.

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