Achieving the composite endpoint of glycated haemoglobin AWARD programme

Sep 13, 2015Diabetes, obesity & metabolism

Meeting blood sugar, weight, and low blood sugar goals with once-weekly dulaglutide in the AWARD program

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Abstract

At 26 weeks, 37-58% of patients on dulaglutide 1.5 mg achieved the of <7.0%, no weight gain, and no hypoglycaemia.

  • Dulaglutide 1.5 mg led to significantly higher odds of reaching the composite endpoint compared to metformin, sitagliptin, exenatide twice daily, and insulin glargine.
  • Patients on dulaglutide 0.75 mg also demonstrated significantly higher odds of achieving the composite endpoint compared to sitagliptin and insulin glargine.
  • No significant difference in the composite endpoint achievement was observed between dulaglutide 1.5 mg and liraglutide 1.8 mg.

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Key numbers

1.5
Higher Odds of Achieving Endpoint with Dulaglutide 1.5 mg
Odds ratio for dulaglutide 1.5 mg vs. metformin
37–58%
Achievement Rate
Percentage of patients reaching <7.0%, no weight gain, no hypoglycaemia
27–49%
Achievement Rate for Dulaglutide 0.75 mg
Percentage of patients achieving the endpoint with dulaglutide 0.75 mg

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