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Abstract
A 32-year-old woman on semaglutide therapy was diagnosed with transient small bowel intussusception.
- Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are effective for diabetes and obesity management.
- Gastrointestinal effects of GLP-1RAs, such as slowed motility, may lead to complications like small bowel obstruction.
- Intussusception, a rare condition in adults, has been infrequently reported in relation to GLP-1RA use.
- In this case, no obstruction or pathological lead point was found, and the condition resolved without intervention.
- These findings suggest a possible association between GLP-1RA therapy and intussusception due to altered gastrointestinal motility.
- Vigilance for rare complications related to GLP-1RAs is advised, especially in patients with gastrointestinal symptoms.
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