Journal of pharmaceutical and biomedical analysis

Urine metabolite changes linked to Guizhi Fuling capsule treatment in rats with primary menstrual pain

Updated

Abstract

A total of 36 potential biomarkers were identified that may be involved in metabolic pathways related to primary dysmenorrhea.

  • Primary dysmenorrhea (PD) is associated with disruptions in various metabolic pathways, including the TCA cycle and lipid metabolism.
  • Guizhi Fuling capsule (GFC) may exert therapeutic effects on PD by regulating multiple metabolic processes.
  • The study utilized advanced techniques to analyze both non-polar and polar metabolites in urine.
  • Identified biomarkers could play a role in the early diagnosis and prediction of primary dysmenorrhea.

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