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The gut microbiome and irritable bowel syndrome: State of art review
The gut microbiome and irritable bowel syndrome: current understanding
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Abstract
Irritable bowel syndrome (IBS) involves multiple factors with gut microbiota playing a significant role.
- Dysmotility, dysregulation of the brain-gut axis, altered intestinal microbiota, and visceral hypersensitivity are major contributors to IBS.
- Individuals with IBS often exhibit a disruption in the balance of gut microbiota.
- The host immune system interacts with metabolic products of gut microbiota, influencing gastrointestinal health.
- Probiotics, prebiotics, and antibiotics may help manage IBS symptoms by modulating these interactions.
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