Gut microbiota and neuropsychiatric disorders: Implications for neuroendocrine-immune regulation

Sep 20, 2021Pharmacological research

Gut bacteria and brain disorders: Links to hormone and immune system regulation

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Abstract

Gut microbiota dysbiosis is linked to neuropsychiatric disorders.

  • Altered microbial community composition and diversity have been observed in individuals with neuropsychiatric disorders.
  • The precise pathways by which intestinal microbiota impact these disorders are not well understood.
  • The relationship between gut microbiota and neuropsychiatric disorders is thought to involve complex interactions between neuroendocrine and immune systems.
  • Evidence suggests that the microbiome-gut-brain axis plays a significant role in this interaction.
  • Clinical and preclinical studies have highlighted the potential influence of gut microbiota on mood disorders and neurodevelopmental disorders.

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