Imbalance of gut bacteria after cardiac arrest: causes, health impacts, and possible treatments

Alterations in gut microbiota composition after cardiac arrest may be associated with multi-organ dysfunction and poor neurological outcomes.

• Post-cardiac arrest syndrome involves systemic ischemia-reperfusion injury that can lead to complex health issues.
• Changes in gut bacteria following cardiac arrest are linked to increased inflammation and immune system problems.
• Impaired intestinal barrier function may contribute to neurological injuries through the gut-brain axis.
• Emerging evidence suggests potential connections between specific microbial signatures and clinical outcomes.
• Microbiota-targeted therapies, like probiotics and prebiotics, could offer new treatment strategies, though direct evidence in PCAS is still limited.

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