Gastroenterology clinics of North America

Gut Bacteria and Problems in Liver Disease

Updated

Abstract

Dysbiosis is associated with endotoxemia and liver injury due to nonalcoholic steatohepatitis and alcohol.

  • Chronic liver disease and cirrhosis complications are increasingly common worldwide.
  • The gut-liver axis plays a critical role in mediating these complications.
  • Culture-independent techniques have enabled widespread analysis of the gut microbiome.
  • Changes in microbiome composition and function occur with cirrhosis progression and treatment.
  • Gut microbiota may serve as predictors for significant outcomes in cirrhosis.

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