Gut Microbiota and Complications of Liver Disease

Dysbiosis is associated with endotoxemia and liver injury due to nonalcoholic steatohepatitis and alcohol.

• Chronic liver disease and cirrhosis complications are increasingly common worldwide.
• The gut-liver axis plays a critical role in mediating these complications.
• Culture-independent techniques have enabled widespread analysis of the gut microbiome.
• Changes in microbiome composition and function occur with cirrhosis progression and treatment.
• Gut microbiota may serve as predictors for significant outcomes in cirrhosis.

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