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Gut microbiota and nonalcoholic steatohepatitis
Gut bacteria linked to fatty liver disease not caused by alcohol
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Abstract
Elevated endotoxin levels in the blood may play a significant role in the pathology of nonalcoholic steatohepatitis (NASH).
- Nonalcoholic fatty liver disease (NAFLD) can progress to serious liver conditions like cirrhosis and cancer.
- The incidence of NAFLD, particularly NASH, is steadily increasing.
- Current effective treatments primarily involve dietary changes and exercise.
- Next-generation sequencing technology is revealing insights into the intestinal microbiome in NAFLD/NASH.
- Intestinal bacterial imbalance may contribute to NASH by increasing intestinal permeability and endotoxin levels.
- Targeting intestinal permeability may offer a new approach for treating NAFLD/NASH.
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