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Gut microbiota: An intermediary between metabolic syndrome and cognitive deficits in schizophrenia
Gut bacteria link metabolism problems and thinking difficulties in schizophrenia
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Abstract
The gut microbiome is associated with behaviors and psychiatric conditions through the gut-brain axis.
- Communication between the gut microbiome and the central nervous system involves neuronal, endocrine, and immunological mechanisms.
- Atypical antipsychotic drugs (AAPDs) may alter microbiome abundance, potentially leading to adverse effects or worsening of psychiatric disorders.
- The gut microbiome's regulatory effects have been noted in several psychiatric disorders, including anxiety and depression.
- Limited evidence exists regarding the role of microbiota in AAPDs-induced metabolic syndrome and cognitive disorders.
- Prebiotics and probiotics are recognized tools for managing metabolic disturbances and cognitive deficits.
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